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NIA News: AD Research Update

VITAL, Other AD Trials Seek Participants

March 2003

The ADEAR Center announces the addition of three research studies to our Clinical Trials Database. These large, multi-site studies are currently underway and recruiting volunteers at multiple sites in the U.S. and elsewhere.

Click on the study title below to go to its complete description and list of sites.

• NEW! VITAL - VITamins to slow ALzheimer's disease (Homocysteine study) - seeks 400 participants age 55 or older with mild to moderate AD to test whether reduction of homocysteine levels with high-dose folate (folic acid), B6 and B12 vitamins will slow the rate of cognitive decline in persons with AD. Duration of treatment: 18 months. 35 study sites in the U.S. VITAL is sponsored by the Alzheimer's Disease Cooperative Study and funded by the National Institute on Aging.


• Vitamin E in Aging Persons with Down Syndrome - three-year study to investigate whether the administration of vitamin E, which has been shown to delay the progression of Alzheimer's disease, will slow the rate of cognitive/functional decline in persons with Down syndrome. The study seeks 400 individuals with Down syndrome, age 50 or older. Trial sites in the U.S., Australia, Canada, and England. Sponsored by the National Institute on Aging.


• COGNIShunt® System for Alzheimer's Disease - Industry-sponsored study of the effect on the progression of Alzheimer's Disease of a surgically implanted shunt (tube) to increase the flow of cerebrospinal fluid and improve the clearance of potential neurotoxins. The 18-month study seeks 250 participants, age 62 or older, with AD.

For information on additional AD studies, go to the ADEAR Clinical Trials Database.

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