Alzheimer's Disease Education and Referral Center

Clinical Trials In The News

These Clinical Trials have been featured in recent newspaper or magazine articles, or on the radio or TV:

  • Alzheimer's Disease Neuroimaging Initiative 2 (ADNI2) Study – The Alzheimer's Disease Cooperative Study is expanding on the research begun with the Alzheimer's Disease Neuroimaging Initiative (ADNI) in 2004 and continued with ADNI-GO in 2010. The goal of the original ADNI study was to define biomarkers for use in clinical trials to determine the best way to measure treatment effects of AD; the goal of ADNI-GO was to use biomarkers to identify AD at an earlier stage of mild cognitive impairment (MCI), when symptoms are milder. ADNI2 extends the work of ADNI1 and ADNI-GO to understand the progression of AD. Researchers are looking for 550 additional volunteers between the ages of 55 and 90 for all cohorts--cognitively normal, with early MCI, late MCI, or AD. For more information, click on the trial name above to see the complete record and list of participating sites.

  • Gammaglobulin Alzheimer’s Partnership (GAP) Study – The Alzheimer's Disease Cooperative Study has begun recruiting participants for a passive immunization trial of intravenous immunoglobulin (IGIv) for reducing brain amyloid. IGIv is a well-known treatment with an established safety record, approved for use for other indications for more than 25 years. Forty sites are expected to participate through a partnership with Baxter Pharmaceuticals, recruiting 360 individuals between the ages of 50 to 89 with probable AD. Most sites will use home-health nurses to administer the IGIv bi-weekly for 72 weeks. Sign up for the IGIV Email Alert to receive updates on this study and the addition of new sites.

  • Nerve Growth Factor in Alzheimer's Disease – The Alzheimer's Disease Cooperative Study, in partnership with Ceregene, is now recruiting participants for a Phase II clinical study of Ceregene's CERE-110, a gene therapy product designed to deliver nerve growth factor (NGF) to the brain for the treatment of Alzheimer's disease (AD).

AD Genetics Study Brochure


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